WebFeb 2, 2013 · The MUC1-C cytoplasmic domain also functions as a substrate for EGFR phosphorylation on the Y 46 EKV motif . In turn, pYEKV functions as a binding site for the SRC SH2 ... Stimulation of normal human mammary epithelial cells with TNFα has been shown to be associated with binding of RelA to the MUC1 promoter and induction of … WebApr 5, 2016 · The N-terminal RxxRxRxxC motif of RelA is a functional element of the DNA-binding L1 loop that provides a DNA sugar-phosphate backbone and base-specific contacts (31, 32). Although R30 does not directly contact DNA ( Fig. S2 ), it is located within the RxxRxRxxC motif of the L1 loop in close proximity to the DNA-contacting R33 and R35.
RELA binds already-active enhancers "with" or "without" a …
WebMay 25, 2016 · Novel binding site for RelA on the ribosome. In the RelA-SRC, RelA is bound in the A-site of the ribosome and interacts with a tRNA that has adopted an A/T-tRNA-like conformation (Figure 2A and B), similar but distinct to that observed during decoding when the EF-Tu delivers the aminoacyl-tRNA to the A-site of the ribosome (Figure 2C). WebDownload scientific diagram a DNA binding motifs enriched for C11orf95 fus1 and C11orf95-RELA fus1 and C11orf95-RELA 1425 in G16-3, G16-4 and BXD-1425-EPN cells, respectively. b Reporter assay. metal armor fallout 2
RELA Gene - GeneCards TF65 Protein TF65 Antibody
WebJan 18, 2008 · More than 200 clones were analyzed in two independent experiments and the results were merged together after a careful statistical analysis (see Supplementary … WebSep 10, 2024 · S4 Fig. Characterization of RELA binding and motif analysis of genes whose RNA levels were increased by dnIκBα ... or within 50 kb of the transcription start site. RELA-binding genes that were up-regulated ≥2-fold at either 1 or 4 h are shown in A. RELA-binding genes that were down-regulated ≥2-fold at either 1 or 4 h are ... WebFeb 22, 2012 · Characterization of the motif recognized in Gemin5 helped in the identification of novel targets of this protease in mammalian cells. Interestingly, the list of proteins retrieved from databases with this motif includes RNA-binding proteins, DNA-binding proteins and several factors involved in cell cycle arrest, differentiation and … metal armored cable