Web29 apr. 2024 · Natural killer (NK) cells are potent innate immune system effector lymphocytes armed with multiple mechanisms for killing cancer cells. Given the dynamic … Webproduction by NK cells [22], it is not known whether the two major effector functions of NK cells—the killing and cytokine secretion—are coordinated on target cells to further enhance the immune surveillance by NK cells. We show here that the productions of IFN- and TNF- by NK cells are functionally linked to their cytolytic activities.
Cytokine-enhanced cytolytic activity of exosomes from NK Cells
Web8 jan. 2024 · We previously reported that PMFs potentiate the cytolytic activity of the human leukemic natural killer (NK) cell line KHYG-1, in part by increasing expression of granzyme B (GrB) and interferon-γ (IFN-γ) [6 ], which are known to potentiate NK cell activity. However, the critical target proteins and mechanisms of action of PMFs are … Web18 sep. 2024 · Overview. Natural Killer (NK) cells are described as a type of toxic lymphocytes that are critical to the immune system [ 1 ]. NK cells are produced in the bone marrow, lymph nodes, spleen, tonsils, and thymus, … all 文章生成器
Transcription factors involved in the regulation of murine NK cell ...
Web1 dec. 2009 · NK lytic-associated molecule (NKLAM) is a protein involved in the cytolytic function of NK cells. It is weakly expressed in resting NK cells but upon target cell … Web2 aug. 2024 · Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-tumor and anti-viral responses, and therefore possess promising clinical … Web1 jul. 2004 · Cytolytic Potential of NK Cells from VV and FF Donors in Response to Optimal FcγRIIIa Stimulation. As expected, Daudi cells were resistant to lysis in the absence of rituximab but were killed efficiently by PBMCs and peripheral blood lymphocytes in the presence of 0.2 μg/ml rituximab (not shown). all播放器