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Web27 sep. 2024 · IgM deficiency has been reported in patients with many autoimmune diseases treated with Rituximab (RTX). It has not been studied, in detail, in autoimmune mucocutaneous blistering diseases (AIMBD). Our objectives were: (i) Examine the dynamics of IgM levels in patients with and without RTX. (ii) Influence of reduced serum IgM levels … Web8 mrt. 2024 · Immunoglobulin (Ig) therapy is recommended in guidelines for the treatment of various neurologic diseases and is a first-line treatment for chronic inflammatory demyelinating polyneuropathy (CIDP), Guillain-Barré syndrome (GBS), multifocal motor neuropathy (MMN), and rescue therapy for worsening myasthenia gravis (MG) ( 1, 2 ). Web16 mrt. 2024 · HMW reduction was to ~8%, and LMW fragments were removed completely. This gave a total removal for the process (Figure 5) of HMW to ~12% and LMW to 6.89% from harvest to CEX elution. Table 2: Removal of high– and low–molecular-weight (HMW, LMW) variants during process runs against harvest taken from worst-case conditions; NA … mote biblical meaning