High affinity copper uptake protein 1-like

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August undefined, 2024

Web8 de abr. de 2024 · Water soluble CB[7]-PEG conjugate still maintains a high affinity for the N-terminal Phe of insulin (K d = 2.1 ± 0.3 μM) like unmodified CB[7]. The pendant PEG chain of at least 30 kDa in CB[7]-PEG conjugate didn't alter the affinity due to steric hindrance of CB[7] for insulin. WebHigh affinity copper uptake protein 1 Kind protein Organism Humans Protein. Name UniProt ID; High affinity copper uptake protein 1: O15431: Details: Drug Relations …

High affinity copper uptake protein 1 (pig) - PubChem

Web21 de abr. de 2011 · COPT7 alone could mediate a high-affinity Cu uptake in the yeast mutant. None of the seven COPTs alone or in cooperation could complement the phenotypes of S. cerevisiae mutants that lacked the transporter genes either for iron uptake or for zinc uptake. WebHigh affinity copper uptake protein 1 Gene SLC31A1 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 190 Protein existence Evidence at … hover over icons in taskbar windows 1

Deregulated copper transport affects Arabidopsis development …

Web22 de ago. de 2024 · Crystal structure of the high-affinity copper transporter Ctr1 in complex with Cu (I) PDB DOI: 10.2210/pdb6M98/pdb Classification: TRANSPORT PROTEIN Organism (s): Salmo salar, Escherichia coli Expression System: Komagataella phaffii GS115 Mutation (s): Yes Membrane Protein: Yes PDBTM MemProtMD mpstruc … WebHuman CTR1 is a high-affinity copper transporter that also mediates the uptake of the anticancer drug cisplatin by largely unknown transport mechanisms. Here we report the 6 … WebCopper is an essential cofactor for key processes in plants, but it exerts harmful effects when in excess. Previous work has shown that the Arabidopsis (Arabidopsis thaliana) COPT1 high-affinity copper transport protein participates in … how many grams in one egg yolk

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High affinity copper uptake protein 1 (pig) - PubChem

WebHigh affinity copper uptake protein 1: Synonyms: Copper transporter 1; Solute carrier family 31 member 1; hCTR1; Gene Name: SLC31A1: Protein Type: Transporter: Biological Properties; ... structure of the human copper transporter CTR1 at 6-A resolution reveals a compact trimer with a novel channel-like architecture. WebCopper is imported into eukaryotic cells through high-affinity copper transporters of the family of Ctr permeases. 9 To date, Ctr transporters are the best-characterized system … hover over image on macbookWeb22 de out. de 2024 · One may speculate about copper speciation and/or mechanisms of copper uptake and release. Apart from trafficking in complex with various neurotransmitters, carrier peptides and proteins, or as part of the protein cargo of extracellular vesicles there is also the potential for copper uptake as a result of … hover overs in powerpoint

"WebGene ID: 102804936, updated on 5-Feb-2024. Summary Other designations. high affinity copper uptake protein 1-like " - High affinity copper uptake protein 1-like

High affinity copper uptake protein 1-like

High affinity copper uptake protein 1 - Wikipedia

WebChemokines and chemokine receptors have been recognized as critical signal components that maintain the physiological functions of various cells, particularly the immune cells. The signals of chemokines/chemokine receptors guide various leukocytes to respond to inflammatory reactions and infectious agents. Many chemokine receptors play supportive … WebLOC106138791 high affinity copper uptake protein 1-like [] Gene ID: 106138791, updated on 13-Feb-2024. Summary Other designations. high affinity ...

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WebThe affinity measured by Km value for the drugs transported by their corresponding DTs were unified to the unit of micromolar 4. 2D and 3D Structures of Small Molecular Drugs The structures of the small molecular drugs transported by DTs were drawn and were standardized in the .sdf format (both 2D and 3D) 5. Web15 de abr. de 2024 · Protein target information for High affinity copper uptake protein 1 (pig). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

Web11 de abr. de 2024 · Thiamine is metabolized into the coenzyme thiamine diphosphate (ThDP). Interrupting thiamine utilization leads to disease states. Oxythiamine, a thiamine analogue, is metabolized into oxythiamine diphosphate (OxThDP), which inhibits ThDP-dependent enzymes. Oxythiamine has been used to validate thiamine utilization as an … Web9 de jun. de 2024 · ATP7A, copper-transporting ATPase 1; ATP7B, copper-transporting ATPase 2; ATOX1, copper transport protein ATOX1; BBB, blood-brain barrier; CCS, copper chaperone for superoxide dismutase; CNS, central nervous system; CP, ceruloplasmin; CTR1, high affinity copper uptake protein 1; CTR2, probable low …

Web11 de abr. de 2024 · Several lines of evidence presented here strongly suggest that the first histidine (His43) upstream from TMD1 is absolutely required for the copper transport activity of COPT1 protein. Firstly, deletion of 43 residues, but not 41 residues, of the extracellular N-terminus, completely blocked high affinity copper uptake of COPT1. WebHigh affinity copper uptake protein 1 is a protein that in humans is encoded by the SLC31A1 gene.[5][6] For faster navigation, this Iframe is preloading the Wikiwand page …

Web11 de mai. de 2024 · At physiological pH, NGF peptides bind one equivalent of copper ion with higher affinity of Aβ and lower than hCtr1 peptide fragments. Therefore, in the synaptic cleft, NGF may act as a potential copper chelating molecule, ionophore or chaperone for hCtr1 for metal uptake.

WebHigh affinity copper uptake protein 1 Gene SLC31A1 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 190 Protein existence Evidence at … hover over the face and press the space bar hover overlay effectsWebProtein target information for High affinity copper uptake protein 1 (house mouse). Find diseases associated with this biological target and compounds tested against it in … hover over text qualtricsWeb27 de mar. de 2024 · Copper (Cu) is an essential trace element for growth and development and abnormal Cu levels are associated with anemia, metabolic disease and cancer. … hover overlay bootstrapWebencode a high affinity copper uptake process and was found to be 29% identical at the primary structure level with Ctr1 from yeast. The human protein was, however, substantially smaller than the yeast protein, being composed of 190 amino acids as compared with 406 amino acids (see Fig. 1). hCTR1 is on the how many grams in one mol of glucoseWebThese high-affinity copper transporters exist in all eukaryotes and their discovery has provided new insights into how cells acquire and regulate this essential nutrient. The … hover over text in accessWebHigh affinity copper uptake protein 1 Gene SLC31A1 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 190 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Download Add a publication Entry feedback Function how many grams in one hectogram