Cisplatin research

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August undefined, 2024

Web2 days ago · Cisplatin is used successfully in the chemotherapy of testicular cancer. However, patients who develop resistance to the cytostatic drug urgently need alternative therapy options. Researchers at... WebSep 23, 2016 · The subsequent intracellular signaling pathway analysis indicated that pAkt and p62 expression levels correlated with alterations in the IC50 values for cisplatin in ovarian cancer, providing an...

Mechanisms of Aminoglycoside- and Cisplatin-Induced …

WebApr 14, 2024 · Among the extracellular vesicles, apoptotic bodies (ABs) are only formed during the apoptosis and perform a relevant role in the pathogenesis of different diseases. Recently, it has been demonstrated that ABs from human renal proximal tubular HK-2 cells, either induced by cisplatin or by UV light, can lead to further apoptotic death in … WebCisplatin is a chemotherapy drug. You might have it as a treatment for a number of different types of cancer. You might have cisplatin on its own or in combination with other cancer … how much is new brake pads

FDA approves sodium thiosulfate to reduce the risk of ototoxicity ...

WebCisplatin is an antineoplastic drug used for the treatment of cancer patients with a variety of different malignancies. Application Cisplatin may be used as an analytical reference … WebCisplatin (NSC 119875, Cisplatinum, cis-diamminedichloroplatinum II, CDDP, cis DDP, DDP) is an inorganic platinum complex, which is able to … Webcisplatin It is a treatment for a number of different types of cancer. How GC works These chemotherapy drugs destroy quickly dividing cells, such as cancer cells. How you have GC You have these drugs into your bloodstream (intravenously). You might have treatment through a long plastic tube that goes into a large vein in your chest. how do i choose my medicare plan

Serum platinum levels and cisplatin induced ototoxicity among …

Discovery – Cisplatin and The Treatment of Testicular …

WebCisplatin is one of the most commonly used chemotherapy drugs, treating a wide range of cancer types. Unfortunately, many cancers initially respond to platinum treatment but … WebCisplatin - CAS 15663-27-1, is a platinum coordination complex with potent anti-neoplastic activity. Induces apoptosis in cancer cells, possibly via caspase-3 activation. Synonym … how do i choose stocks to invest inWebAlthough cisplatin, cis-diamminedichloroplatinum(II), has been successfully used in the chemotherapy of cancer for more than 25 years, its biochemical mechanism of action is still unclear. The current accepted paradigm about cisplatin mechanism of action is that the drug induces its cytotoxic proper … how do i circle something in excel

"WebDec 12, 2024 · Cisplatin Adult Medication Share This information from Lexicomp ® explains what you need to know about this medication, including what it’s used for, how to take it, … " - Cisplatin research

Cisplatin research

Overcoming cisplatin resistance of ovarian cancer cells by …

WebCisplatin is a potent anticancer agent that blocks DNA synthesis. Induces apoptosis via p53-dependent and -independent mechanisms. Inhibits X-linked inhibitor of apoptosis protein (XIAP) expression and activates caspase-3. In certain glioma cell lines, sensitizes cells to TNF- α -induced apoptosis. Technical Data M.Wt: 300.05 Formula: WebCisplatin is a chemotherapeutic drug that has been used in the treatment of various types of human cancers such as ovarian, lung, head and neck, testicular and bladder. Cisplatin has demonstrated efficacy against various types of cancers such as germ cell tumors, sarcomas, carcinomas as well as lymphomas.

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WebApr 13, 2024 · The chances of cure with this type of chemotherapy are exceptionally high for testicular cancer. However, in some patients the tumor develops cisplatin resistance, which is associated with a reduced survival rate. To get to the bottom of the causes of cisplatin resistance in testicular cancer, the Bonn research team used CRISPR gene scissors. WebMay 1, 2006 · Abstract and Figures Cisplatin is currently one of the most widely used anticancer drugs in the world. The unlikely events surrounding the discovery of its anticancer activity, subsequent...

WebMost sources say that cisplatin is soluble in water and saline at around 1 mg/ml - 2.5 mg/ml depending on the source. I saw in the attached article (under liposome preparation method) that they ... WebChemical Name. cis-Diaminodichloroplatinum. Biological Activity. Potent anticancer agent that blocks DNA synthesis. Induces apoptosis via p53-dependent and -independent …

WebJan 14, 2024 · Chemotherapy Always Benefits the Cancer Center. Cancer centers significantly mark up chemotherapy drugs, which I cover in the article The Absurd … WebCisplatin is a platinum-based chemotherapeutic that has long since been effective against a variety of solid-cancers, substantially improving the five-year survival rates for cancer patients. Its use has also historically been limited by its adverse drug reactions, or cisplatin-induced toxicities (CITs). Of these reactions, cisplatin-induced nephrotoxicity (CIN), …

WebCisplatin, a chemotherapy drug, is best known for curing testicular cancer. It is also used in the treatment of a wide range of other cancers, including lung, bladder, cervical, and ovarian cancers. Cisplatin and other similar …

Web2 days ago · One of the main problems in chemotherapy using platinum drugs as anticancer agents is the resistance phenomenon. Synthesizing and evaluating valid alternative compounds is challenging. This review focuses on the last two years of progress in the studies of platinum (II)- and platinum (IV)-based anticancer complexes. In particular, the … how do i choose where my obs recordings goWebCisplatin Injection is a sterile, multidose vial without preservatives. Store at 15° to 25°C (59° to 77°F). Do not refrigerate. Protect unopened container from light. The cisplatin remaining in... how do i circle in pdfWebMar 15, 2003 · Abstract. Ovarian cancer is the leading cause of death among women from gynecological malignancies inthe United States. Resistance to the chemotherapeutic agent cisplatin isa major limitation for the successful treatment of ovarian cancer. In an effort to overcome the cisplatin resistance problem in ovarian cancer treatment, we have sought … how much is new iwatchWebResearch Day 2024. Serum platinum levels and cisplatin induced ototoxicity among pediatric germ cell tumor survivors. Lacy Pehlke. MPH, Epidemiology. Co-Authors: Jen … how do i choose the best sitz bathWebJul 1, 2001 · Knowledge of the mechanism of action of cisplatin has improved our understanding of resistance. Decreased intracellular concentration due to decreased drug uptake, increased reflux or increased inactivation by sulfhydryl molecules such as glutathione can cause resistance to cisplatin. Increased excision of the adducts from … how do i circle something in adobeWebThe prevalence of cancer, in the world is increasing steadily. Despite intense research efforts, no approved therapy is yet available. Cisplatin is a chemotherapeutic drug but induces acute tissue injury. Oleuropein (OLE) is a major phenolic compound and used as a possible natural antioxidant, antimicrobial, and anticancer agent. how do i circle a word in wordWebSep 24, 2024 · Cisplatin is a highly effective chemotherapeutic agent used to treat various cancers. Patients are administered controlled doses of cisplatin intravenously as an infusion. Even though cisplatin is very effective at its job, it has its own toxic side effects. how do i choose the best pool deck paint